EnsiliTech ®

Biologicals without refrigeration

It is estimated that more than 25% of vaccines worldwide are wasted, largely due to failures in vaccine cold chain transport and storage.

World Health Organisation

Our Solution

Ensilication® is a patent protected, novel method for encasing thermally unstable biomolecules within a silica network to prevent degradation at temperatures from –80 to +50 °C, and improved shelf-life.

The technology is designed for both existing, and new biopharmaceutical formulations. It produces thermally stable products that do not rely on cold-chain logistics, preventing wastage, improving shelf-life and increasing the accessibility of biological therapeutics and diagnostics globally.

Unlike other stabilisation technologies, ensilication does not rely on lyophilisation or any harsh conditions. The technology is designed for both existing, and new biopharmaceutical formulations. It produces thermally stable products that do not rely on cold-chain logistics.

The Problem

At present, antibodies, vaccines, and other biological products are shipped and stored around the world using a global network of refrigerators and freezers known as the cold chain.

 This network is expensive to operate and prone to failure, resulting in significant levels of spoilage, resulting in 1.5M infants dying each year. Cold chain failures are reported to cost the pharmaceutical industry ~$35B annually.

The cold chain is equally as costly for our planet as it is for human and animal life, being  responsible for up to 90% of vaccination programme emissions, producing over 1.5B tonnes of CO2 in 2021 alone.

 

Applications

Ensilication can be applied to protect a wide variety of biomolecules against environmental degradation, eliminating the cold chain requirements for therapeutic and diagnostic biologicals used in humans, animals, as well as laboratory research.

If you have a specific application or biological in mind, please get in touch and we can discuss the potential of ensilication.

Therapeutic and Diagnostic Antibodies

Anti-microbial Resistance

Vaccines including subunit, viral and virus like, bacterial, and others

Genetic Material

Probiotics and additives

Enzymes

Supported By

 

Get in Touch

We are actively looking for partners to work with us in developing new technologies free from the reliance on the cold chain. If you're interested in finding out more, get in touch below.